What Is Ozempic and How Does It Work?
Ozempic (semaglutide) is a prescription medication originally developed to manage blood sugar levels in people with type 2 diabetes. Today, it’s increasingly prescribed for weight loss, especially in patients with obesity or weight-related health concerns. As a GLP-1 receptor agonist, Ozempic mimics a natural hormone that helps regulate appetite, slow down digestion, and enhance insulin release — all of which support healthier metabolic function. But there are also some Ozempic side effects that make some vary about taking the drug.
Though it’s often confused with Wegovy, which also contains semaglutide, Ozempic is not officially approved in Canada for weight loss. Still, many physicians prescribe it “off-label” when deemed appropriate. Its growing popularity means more people are asking: what Ozempic side effects should I expect?
Common Side Effects of Ozempic
Like any medication, Ozempic comes with a list of potential side effects. While not everyone will experience them, knowing what to expect can make the journey smoother.
Nausea and Digestive Discomfort
Nausea is one of the most commonly reported side effects. It’s usually more pronounced at the beginning or when the dose is increased. Some people also experience vomiting, bloating, or constipation. These symptoms are largely due to how Ozempic slows gastric emptying.
Tips to manage it:
- Eat smaller, low-fat meals
- Stay upright after eating
- Avoid greasy or spicy foods
Headaches, Fatigue, and Dizziness
These symptoms can occur as your body adjusts to the medication and changes in blood sugar levels. They’re typically mild and tend to decrease over time.
Injection Site Reactions
Some users notice redness, swelling, or itchiness where they inject the medication. Rotating injection sites and using proper technique usually helps minimize discomfort.
Rare but Serious Side Effects
While less common, some people may experience more serious side effects such as:
- Pancreatitis
- Gallbladder issues
- Changes in vision
- Kidney problems
It’s important to contact your healthcare provider if you experience severe stomach pain, persistent vomiting, or signs of dehydration.
How to Manage Ozempic Side Effects
Managing side effects is often about preparation, patience, and personalised care. Here’s what can help:
- Start with the lowest dose and increase gradually as advised
- Maintain hydration, especially if experiencing nausea or diarrhoea
- Track symptoms in a journal or app to discuss with your doctor
- Speak up if symptoms interfere with daily life — alternatives or adjustments may be possible
Things to Know Before Starting Ozempic
Who Qualifies for Ozempic in Ontario?
In Ontario, Ozempic is typically prescribed for people with type 2 diabetes. However, when used off-label for weight loss, it’s usually considered for individuals with:
- A BMI of 30 or higher
- A BMI over 27 with health issues like high blood pressure, high cholesterol, or sleep apnoea
Wegovy, a similar medication specifically approved for weight loss, is more suitable for non-diabetic patients. It’s available in Canada under strict eligibility guidelines, and in some cases, may be covered by private insurance plans.
At Modest Medix, we help patients in Ontario understand what options are right for them, including insurance navigation and alternative solutions.
Wegovy vs Ozempic in Canada
While both medications contain semaglutide, they’re approved for different uses:
- Ozempic: Approved for type 2 diabetes (used off-label for weight loss)
- Wegovy: Approved specifically for chronic weight management
Choosing the right option depends on your health goals, eligibility, and insurance coverage — something our clinic team can help assess with you.
How Modest Medix Can Help You
We know this space. Our weight management program is led by physicians who understand these medications inside and out. We’re not here to hand you a script and wish you luck, we help figure out what fits you.
Because here’s what we believe: Medication can help, but it’s just one piece of the puzzle.
Your personalised plan at Modest Medix includes:
- Full medical assessments to see if meds like Wegovy are right for you
- Genetics-based nutrition and lifestyle plans, delivered through our digital app
- Personalised lifestyle coaching backed by your genetic testing
- One-on-one support using Acceptance and Commitment Therapy (ACT)—a proven approach for behaviour change
- Regular follow-ups to track progress, manage side effects, and adjust the plan as needed
Our team of MDs, registered dietitians, and health educators walk with you through every part of the journey: supporting you, not overwhelming you.
Conclusion
Ozempic can be a powerful tool for weight loss — but it’s not without side effects. By understanding what to expect, who qualifies, and how to manage symptoms, you’ll be better equipped to navigate this treatment with confidence.
Support matters. And when you’re ready to start, we’re here to help.
Written by the Modest Medix Clinic Team | Reviewed by Dr. Saima Khan (Dr. Eskay)
